What is XDB C18?

Eclipse XDB-C18 is espe- cially useful for the separation of acidic, basic, and other highly polar compounds by reversed-phase liq- uid chromatography. This special Zorbax silica support (Type B) is designed to reduce or eliminate strong adsorption of basic and highly po- lar compounds.

What is XDB column?

Dextromethorphan. eXtra Dense Bonding (XDB) is key to the exceptional performance of ZORBAX Eclipse XDB columns at intermediate pH (Figure 2). This dense bonding is accom- plished by adding an extra-dense mono- layer of C18, C8, phenyl, or CN-silane to the ultra-pure, fully-hydroxylated, ZORBAX Rx-silica surface.

What is zorbax column?

ZORBAX columns are based on traditional fully porous particles and offer the highest loading capacity and resolution. From ZORBAX Eclipse Plus C18 to sub-2 micron UHPLC columms, a wide selection of stationary phases and particle sizes allows you to fine-tune your selectivity to match your application.

What does C18 mean in HPLC column?

C18 simply means that the molecules contain 18 carbon atoms, so the other atoms in the molecule can vary, leading to significantly different substances. Knowing the characteristics of the compounds that will be run through the C18 columns can help you choose which one will work best for you.

What is the difference between inertsil ODS 3 and ODS 3V?

Inertsil ODS-3V offers all of the outstanding chromatographic benefits of Inertsil ODS-3 with the added benefit of a more thoroughly documented, validated QC procedure consistent with the demands of GLP/GMP compliance.

Are all C18 columns the same?

The different C18 columns are made to allow for different selectivities. Although all your columns are C18 functionalized phases, they will differ in hydrophobicity, peak shape (depending of degree and quality of end-capping and purity of silica) and selectivity and perhaps pore radius.

Which column is more polar C8 or C18?

C18 has 18 carbon atoms while C8 has only 8 carbon atoms. C18 has a longer carbon chain, but C8 has a shorter one. C18 has higher retention while C8 has shorter retention. C18 has higher hydrophobicity, but C8 has a lower hydrophobicity….Follow Pharmaguideline.

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