When do you use Aggrastat?
Aggrastat is indicated for the prevention of early myocardial infarction in adult patients presenting with acute coronary syndromes without ST elevation (NSTE-ACS) with the last episode of chest pain occurring within 12 hours and with ECG changes and/or elevated cardiac enzymes.
How do you administer Aggrastat?
Recommended Dosing & Administration Administer intravenously 25 mcg/kg within 5 minutes and then 0.15 mcg/kg/min for up to 18 hours. In patients with creatinine clearance (CrCl) ≤ 60 mL/min, give 25 mcg/kg bolus within 5 minutes followed by an infusion of 0.075 mcg/kg/min for up to 18 hours.
What type of drug is Aggrastat?
Aggrastat belongs to a class of drugs called Antiplatelet Agents, Cardiovascular; Glycoprotein IIb/IIIa Inhibitors.
What is Aggrastat used for?
TIROFIBAN blocks platelets from forming blood clots. It is used to prevent complications during episodes of chest pain or a heart attack, or during a procedure to treat a blocked artery of the heart.
Can you take heparin and Aggrastat?
AGGRASTAT, in combination with heparin, is indicated for the treatment of acute coronary syndrome, including patients who are to be managed medically and those undergoing PTCA or atherectomy.
How do you reverse tirofiban?
Tirofiban can be stopped before the procedure, but currently there is no available reversible agent. As a result, platelet transfusion may be needed for reversing the effect.
How is argatroban administered?
Initial Dosage: Initiate an infusion of Argatroban Injection at 25 mcg/kg/min and administer a bolus of 350 mcg/kg via a large bore intravenous line over 3 to 5 minutes (see Table 2). Check an activated clotting time (ACT) 5 to 10 minutes after the bolus dose is completed.
What drug class is bivalirudin?
Bivalirudin is a medication used to manage and treat patients undergoing percutaneous coronary intervention for acute myocardial infarction. It is in the direct thrombin inhibitor class of drugs.
How often do you get heparin injections?
Heparin is sometimes injected one to six times a day and sometimes given as a slow, continuous injection into the vein.
When is heparin used?
Heparin is used to prevent blood clots from forming in people who have certain medical conditions or who are undergoing certain medical procedures that increase the chance that clots will form.
What is the brand name for argatroban?
Acova (argatroban) dosing, indications, interactions, adverse effects, and more.
What is the antidote for argatroban?
Like other direct thrombin inhibitors, there is no antidote for argatroban. Argatroban is monitored using the activated partial thromboplastin time (aPTT).
When to use Aggrastat in combination with heparin?
AGGRASTAT® (Tirofiban Hydrochloride Injection Premixed) 9123301 AGGRASTAT® (Tirofiban Hydrochloride Injection) 5 INDICATIONS AND USAGE AGGRASTAT, in combination with heparin, is indicated for the treatment of acute coronary syndrome, including patients who are to be managed medically and those undergoing PTCA or atherectomy.
How long can you take aspirin with Aggrastat?
In clinical studies with the recommended regimen (25 mcg/kg bolus followed by a 0.15 mcg/kg/min maintenance infusion), Aggrastat was administered in combination with aspirin, clopidogrel and heparin or bivalirudin to over 8000 patients for typically ≤24 hours.
How long can you take tirofiban with Aggrastat?
In clinical studies with the recommended regimen (25 mcg/kg bolus followed by a 0.15 mcg/kg/min maintenance infusion), AGGRASTAT was administered in combination with aspirin, clopidogrel and heparin or bivalirudin to over 8000 patients for typically ≤24 hours.
What are the use of Aggrastat in cardiac patients?
Indications and Usage for Aggrastat. Aggrastat® is indicated to reduce the rate of thrombotic cardiovascular events (combined endpoint of death, myocardial infarction, or refractory ischemia/repeat cardiac procedure) in patients with non-ST elevation acute coronary syndrome (NSTE-ACS).