What is isoniazid Tablets BP 300mg?
Isoniazid 300mg Tablet is an antibiotic used for the treatment and prevention of tuberculosis (TB) and inactive (latent) TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body). It works by killing the bacteria that cause tuberculosis.
What are the ingredients in isoniazid?
Isoniazid is an antibacterial available as 100 mg and 300 mg tablets for oral administration. Each tablet also contains as inactive ingredients: colloidal silicon dioxide, lactose monohydrate, pregelatinized starch (corn), povidone and stearic acid.
Which drug class is isoniazid?
Isoniazid is in a class of medications called antituberculosis agents. It works by killing the bacteria that cause tuberculosis.
Which is a serious side effect of isoniazid?
Serious and sometimes fatal liver problems may occur during treatment with isoniazid or after you stop taking this medication, even months after stopping. The risk of liver problems is highest in adults between the ages of 35 and 65.
Who should not use isoniazid?
liver problems. severe liver disease. severe renal impairment. severe nausea and vomiting that has lasted a long time.
Does isoniazid cause liver damage?
Even with monitoring, isoniazid remains a major cause of acute liver failure due to idiosyncratic reactions, and is associated with several instances of acute liver failure and death or emergency liver transplanation in the United States each year.
What does isoniazid do to the body?
Isoniazid is used with other medications to treat active tuberculosis (TB) infections. It is also used alone to prevent active TB infections in people who may be infected with the bacteria (people with positive TB skin test). Isoniazid is an antibiotic and works by stopping the growth of bacteria.
Does isoniazid make you gain weight?
Headache, poor concentration, weight gain, poor memory, insomnia, and depression have all been associated with isoniazid use. All patients and healthcare workers should be aware of these serious side effects, especially if suicidal ideation or behavior are suspected.
Does isoniazid cause skin darkening?
Nonsteroidal anti-inflammatory drugs, antimalarials, amiodarone, cytotoxic drags, tetracyclines, heavy metals and psychotropic drugs are most commonly responsible for hyperpigmentation. A 74-year-old man who had taken antituberculosis drop (rifampin and isoniazid) for 4 months developed generalized hyperpigmentation.
When should I stop taking isoniazid?
If biochemical monitoring is done (generally at monthly intervals initially), isoniazid should be discontinued for any confirmed elevation of ALT above 5 times the ULN (or above 3 times ULN in the presence of symptoms).
How can I protect my liver from medication?
Here are some ways you may be able to prevent it:
- Only take the drugs you need.
- Don’t take supplements that contain herbs that could be toxic to your liver.
- If you take acetaminophen, don’t drink alcohol.
- Follow safety rules if you use any chemicals or solvents at work.
Can TB be cured in 2 months?
Brief Summary: Tuberculosis (TB) is a serious infection that can affect the lungs and other parts of the body. The usual way to treat TB is to take 4 medicines by mouth every day for 2 months, then take 2 of the same medicines for 4 more months, for a total of 6 months.
Is there a 300 mg tablet of isoniazid?
Preventive treatment should be deferred in persons with acute hepatic diseases. Description Isoniazid is an antibacterial available as 100 mg or 300 mg tablets for oral administration. Isoniazid is chemically known as isonicotinyl hydrazine or isonicotinic acid hydrazide.
Are there any inactive ingredients in isoniazid tablets?
Preventive treatment should be deferred in persons with acute hepatic diseases. Isoniazid is an antibacterial available as 100 mg and 300 mg tablets for oral administration. Each tablet also contains as inactive ingredients: anhydrous lactose, calcium stearate, colloidal silicon dioxide, microcrystalline cellulose, and stearic acid.
What kind of Medicine is isoniazid used for?
What Isoniazid is for Isoniazid belongs to a group of medicines called antibacterials. Isoniazid works by killing bacteria that cause tuberculosis (also known as TB). Isoniazid is used to treat tuberculosis inside the lungs (pulmonary TB) and outside the lungs (extra-pulmonary TB)…
What are the side effects of isoniazid injection?
Isoniazid is contraindicated in patients who develop severe hypersensitivity reactions, including drug-induced hepatitis; previous isoniazid-associated hepatic injury; severe adverse reactions to isoniazid such as drug fever, chills, arthritis; and acute liver disease of any etiology.