By What is the purpose of dehydration of 2-methylcyclohexanol?
The dehydration of 2-methylcyclohexanol proceeds through an E1 elimination. The acid catalyst protonates the hydroxy group converting it into a good leaving group, a neutral molecule of water. The water departs on its own, generating a carbocation, which quickly eliminates a beta-proton to form a double bond.
What is the major product of dehydration of 2-methylcyclohexanol?
1- methylcyclohexene
Conclusions: It is evident that the dehydration of 2-methylcyclohexanol in H3PO4 gave 1- methylcyclohexene as the major product, as predicted by Saytzev (more substituted C=C being more stable).
What is the limiting reagent in the dehydration of 2-methylcyclohexanol?
Table of Reactants
| Compound | MW | mol |
|---|---|---|
| Cis 2-methylcyclohexanol | 114.19 | .041 TOTAL *limiting reagent |
| Trans 2-methylcyclohexanol | 114.19 | |
| H2SO4 Sulfuric acid 9M | 98.08 | 2.65 |
What is the final step in the mechanism of the dehydration of 2-methylcyclohexanol?
Furthermore, the greater stability of the tertiary carbocation over the secondary cation makes the final step of the reaction thermodynamically somewhat reversible, so that if the reaction is carried out over longer times, a relatively larger fraction of methylenecyclohexane (compared to 1-methylcyclohexene) is …
What are the safety warnings for 2-methylcyclohexanol?
May cause respiratory tract irritation. Skin May be harmful if absorbed through skin. May cause skin irritation. Eyes May cause eye irritation.
What are the safety warnings for 2-Methylcyclohexanol?
What is the first mechanistic step in the acid promoted dehydration of 2-methylcyclohexanol?
Mechanism. The first step in the mechanism is protonation of the alcohol group by the acid (slightly exothermic). The second step is the loss of water to form the carbocation (highly endothermic). The final step is removal of a beta hydrogen by base (water) to form the alkene (exothermic).
Is 2-Methylcyclohexanol toxic?
Inhalation May be harmful if inhaled. May cause respiratory tract irritation. Ingestion May be harmful if swallowed. Skin May be harmful if absorbed through skin.