By What drugs should not be taken with grapefruit?
Examples of common medications that interact with grapefruit juice include certain statin cholesterol drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin).
What drug classes interact with grapefruit juice?
Prominent medications known to interact with grapefruit include statins, antiarrhythmic agents, immunosuppressive agents, and calcium channel blockers. There are equally effective alternatives to these drug classes that do not have the potential to interact with grapefruit.
Does grapefruit juice cause drug toxicity?
One whole grapefruit, or a small glass (200 mL, 6.8 US fl oz) of grapefruit juice, can cause drug overdose toxicity. Fruit consumed three days before the medicine can still have an effect.
Which of the following drugs is unlikely to interact significantly with grapefruit juice?
Grapefruit juice did not interact with a number of other medications. These include prednisone [69], acenocoumarol [74], quinidine [75] and theophylline [76]. This is not unexpected since these drugs already have high or almost complete oral bioavailability.
Why can’t you have grapefruit with blood pressure medicine?
Calcium channel blockers They’re used as part of the treatment of conditions such as high blood pressure (hypertension) and coronary heart disease. Grapefruit juice interacts with some calcium channel blockers and increases the level of the medicine in your blood.
What blood pressure meds should not be taken with grapefruit?
Here are examples of some types of drugs that grapefruit juice can cause problems (interact) with:
- Some statin drugs to lower cholesterol, such as Zocor (simvastatin) and Lipitor (atorvastatin).
- Some drugs that treat high blood pressure, such as Procardia and Adalat CC (both nifedipine).
Is grapefruit bad for high blood pressure?
Grapefruit contains compounds that may interfere with how your body absorbs some drugs, including some blood pressure medicines. It can leave too much or too little of the drug in your bloodstream, which may be dangerous. Always ask your doctor or pharmacist if grapefruit could affect the medicine you’re taking.
Why is grapefruit bad for high blood pressure?
What are the side effects of drinking grapefruit juice?
Eating a grapefruit or consuming its juices while taking certain medications could lead to gastrointestinal bleeding, kidney failure, depressed breathing and sudden death, warns a new paper in the Canadian Medical Association Journal.
What is the problem with grapefruit and medications?
Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer. The result: too much drug in your body.
Does grapefruit juice affect blood pressure medicine?
Though grapefruit does not interfere with most blood pressure medications, it can cause a few medications to overcorrect blood pressure.
Can grapefruit clear plaque in arteries?
In one study, animals fed a high-cholesterol diet plus grapefruit pectin had 24 percent narrowing of their arteries, versus the control with 45 percent narrowing. In other words, the pectin binds to cholesterol and helps to remove arterial buildup.