How does TURP cause hyponatremia?
Hyponatremia after transurethral resection of the prostate (TURP) or hysteroscopy is caused by absorption of irrigants, glycine, sorbitol, or mannitol, contained in nonconductive flushing solutions used for those procedures. The degree of hyponatremia is related to the quantity and rate of fluid absorbed.
How do you treat TURP syndrome?
Management of severe TURP syndrome. Diuretic therapy (e.g. i.v. furosemide 40 mg) is only recommended to treat acute pulmonary oedema caused by the transient hypervolaemia. Furosemide worsens hyponatraemia, but is effective at removing free water.
What is the cause of TURP syndrome?
Transurethral resection of prostate (TURP) syndrome is a systemic complication of transurethral resection of the prostate or bladder tumours, caused by excessive absorption of electrolyte-free irrigation fluids.
Why glycine is used in TURP?
2.2%: Glycine, an endogenous amino acid has been suggested as a suitable irrigating fluid considering its many advantages, including the low cost, though not as cheap as sterile water. Glycine is isotonic with plasma only at a concentration of 2.2%, but the side effects of glycine at this concentration are more.
What is post TURP syndrome?
Abstract. Absorption of large volumes of irrigation fluid during transurethral resection of the prostate (TURP) can produce hyponatremia, coma, blindness, and cardiorespiratory depression. This has been termed the “post-TURP syndrome.” The pathophysiology and management of this syndrome are controversial.
What are the complications of TURP?
What are the risks of a TURP?
- Bladder injury.
- Bleeding.
- Blood in the urine after surgery.
- Electrolyte abnormalities.
- Infection.
- Loss of erections.
- Painful or difficult urination.
- Retrograde ejaculation (when ejaculate goes into the bladder and not out the penis)
Is pulmonary edema a symptom of TURP syndrome?
Case Presentation. We report a patient who suffered severe TURP syndrome after transurethral resection of the prostate procedure. Clinical manifestations were pulmonary edema and respiratory failure.
When does TURP syndrome occur?
It may present as early as 15 min after resection starts or as late as 24 h after operation. Severe TURP syndrome is now rare; however, it carries a mortality of up to 25%. Our patient’s perioperative sodium concentration was 90 mEq/l and he had non-specific symptoms due to hyponatremia.
What is the best time to take glycine?
Taking glycine before bedtime for 2-4 days seems to improve sleep in people with poor sleep quality. Taking glycine before bedtime might also reduce feelings of tiredness the following day after a shortened night of sleep.
How long does it take to fully recover from TURP surgery?
It usually takes between 3 and 6 weeks to fully recover from a TURP. Your surgeon or GP will advise you about when it’s safe to return to your normal activities.
Does TURP cause impotence?
However, TURP, the standard surgical therapy for the relief of LUTS, is reported to cause erectile dysfunction (ED), although some patients with preexisting ED reported improved erectile function after TURP.