What is complex coacervation?

Complex coacervation is a highly promising microencapsulation technique that is extensively employed in pharmaceutical, food, agriculture and textile industries. The process involves the interaction of oppositely charged polyelectrolytes in aqueous form.

What is coacervation in pharmacy?

Abstract. Phase separation or coacervation is one of the oldest and perhaps the most widely used method of microencapsulation. This paper discusses phase separation or coacervation as a technique of preparing microcapsules.

What causes coacervation?

The common driving force for the coacervation method is electrostatic attraction between oppositely charged molecules. In addition to the electrostatic interactions between biopolymers of opposite charges, hydrogen bonding and hydrophobic interactions inversely affect complex coacervation.

What is meant by Coacervation?

Coacervation is a process during which a homogeneous solution of charged macromolecules undergoes liquid–liquid phase separation, giving rise to a polymer-rich dense phase at the bottom and a transparent solution above.

How many phases are there while microencapsulation by coacervation?

2.6 Complex coacervation It is a process that involves phase-separation to form two separate liquid phases consisting of a polymer-rich phase and polymer-depleted phase, referred to as coacervate and equilibrium solution respectively (Timilsena et al., 2017).

Why coacervates are called primitive cell?

⟹Coacervates are the large colloidal cell like aggregates of complex organic compounds. ⟹The large orgainc molecules synthesize abiotically on primitive earth formed large colloidal aggregates or coacervates. ⟹Hence they are considered as primitive cell.

What is coacervate in Bengali?

coacervate in English droplets of liquid that form in a lyophilic solution before the precipitation of solid material. english. coacervate ⇄ noun coacervation. english.

What can chitosan be used for in food?

Chitosan (CS) [(1-4)-2-amino-2-deoxy-β-d-glucan] as a linear cationic polysaccharide, began to be noticed in recent years due to its great potential in food processing. Yuan, Wan, Yin, and Yang (2013)suggested that chitosan can be used in food emulsion as a stabilizing agent and antibacterial agent.

Which is a potential application of chitosan nanoparticles?

The prepared particles have been exploited as a potential carrier for different therapeutic agents such as peptides, proteins, vaccines, DNA, and drugs for parenteral and nonparenteral administration. Therapeutic agent-loaded chitosan micro- or nanoparticles were found to be more stable, permeable, and bioactive.

Are there any side effects when taking Chitosan by mouth?

When taken by mouth, chitosan might cause mild stomach upset, constipation, or gas. When used on the skin, chitosan can cause irritation. Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking chitosan by mouth if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

What happens if you take chitosan with warfarin?

Warfarin is a blood thinner. There is some concern that taking chitosan might increase the blood thinning effects of warfarin (Coumadin). Taking chitosan with warfarin (Coumadin) could increase the chance of bruising or bleeding. If you take warfarin, avoid taking chitosan.