What is CK-MB fraction?

What is being tested? Creatine kinase-MB (CK-MB) is a form of an enzyme found primarily in heart muscle cells. This test measures CK-MB in the blood. CK-MB is one of three forms (isoenzymes) of the enzyme creatine kinase (CK).

What does CK-MB tell you?

This test measures the amount of an isoenzyme of creatine kinase (CK) in your blood. It is called CK-MB. Your body makes 3 forms of CK, including CK-MB. CK is found in the heart, muscles, and other organs.

What is a normal CK-MB level?

3 to 5%
A significant concentration of CK–MB isoenzyme is found almost exclusively in the myocardium, and the appearance of elevated CK–MB levels in serum is highly specific and sensitive for myocardial cell wall injury. Normal reference values for serum CK–MB range from 3 to 5% (percentage of total CK) or 5 to 25 IU/L.

What are normal levels for troponin and CK-MB?

Cardiac Injury Markers

Current Assay (Dade Behring/Opus Plus)
Myoglobin Normal < 82 ng/ml
CK-MB Normal < 5.0 ng/ml
Troponin-I Detection Limit = 0.5 ng/ml Abnormal > 2.0 ng/ml Borderline – Not detected Not flagged abn = 0.8 – 2.0 ng/ml Flagged abn > 2.0 ng/ml

What is CPK normal range?

Normal Results Total CPK normal values: 10 to 120 micrograms per liter (mcg/L)

How is CK-MB calculated?

Contact your healthcare worker if you have any questions. The following are considered to be normal results for this test: CK-MB (mass) index is a calculated number = [CK-MB (ng/mL) ÷ total CK (Units/L)] x 100 [4][5][6].

What is a dangerously high CK level?

In rhabdomyolysis, the CK levels can range anywhere from 10 000 to 200 000 or even higher. The higher the CK levels, the greater will be the renal damage and associated complications.

What is a bad CK level?

In the absence of specific myocardial or brain infarction, physical trauma, or disease, serum CK levels greater than 5,000 U/L are generally considered to indicate serious disturbance to muscle [10].

What is a normal CK?

In a healthy adult, the serum CK level varies with a number of factors (gender, race and activity), but normal range is 22 to 198 U/L (units per liter). Higher amounts of serum CK can indicate muscle damage due to chronic disease or acute muscle injury.

How can I lower my CK-MB level?

In conclusion, nitroglycerin reduces CK and CK-MB release and hence calculated infarct size, particularly when treatment is begun within the first 8 hours after onset of symptoms.

Why is troponin better than CK-MB?

Results: We found that (1) troponin I is a better cardiac marker than CK-MB for myocardial infarction because it is equally sensitive yet more specific for myocardial injury; (2) troponin T is a relatively poorer cardiac marker than CK-MB because it is less sensitive and less specific for myocardial injury; and (3) …

What are the symptoms of high CK levels?

Elevated creatine kinase may accompany symptoms that are related to other body systems including:

  • Confusion or loss of consciousness, even for a brief moment.
  • Garbled or slurred speech.
  • Loss of vision or vision changes.
  • Muscle aches and pains.
  • Muscle stiffness.
  • Paralysis.
  • Sudden weakness or numbness on one side of the body.