What does a positive ANA in a child mean?

The ANA test is a laboratory study that can be ordered by your child’s physician as part of the evaluation for autoimmune or rheumatologic conditions. When this test result is positive (abnormal), it can create a great deal of anxiety both to the parent, patient and the ordering provider.

Can leukemia cause a positive ANA?

Background: Serum antinuclear antibodies (ANAs) are positive in some patients with chronic lymphocytic leukemia (CLL), but the prognostic value of ANAs remains unknown.

Can you test positive for ANA and not have lupus?

While most people with lupus have a positive ANA test, most people with a positive ANA do not have lupus. If you test positive for ANA , your doctor may advise more-specific antibody testing.

What infections cause a positive ANA?

Conditions that usually cause a positive ANA test include:

  • Systemic lupus erythematosus.
  • Sjögren’s syndrome — a disease that causes dry eyes and mouth.
  • Scleroderma — a connective tissue disease.
  • Rheumatoid arthritis — this causes joint damage, pain, and swelling.
  • Polymyositis — a disease that causes muscle weakness.

Can positive ANA go away?

The new criteria require that the test for antinuclear antibody (ANA) must be positive, at least once, but not necessarily at the time of the diagnosis decision because an ANA can become negative with treatment or remission.

What cancers cause elevated ANA?

Neoplastic diseases may cause positive ANA. Some authors have described that ANA is found in the sera from lung, breast, head and neck cancer patients as frequently as in RA and SLE 3, 4, 5. Chapman et al. 6 has suggested that in breast cancer they may be used as an aid to early diagnosis.

Can infection cause elevated ANA?

Antinuclear antibodies (ANA) are present in many systemic autoimmune conditions such as systemic lupus erythematosus (SLE). However, a positive ANA test may also be seen with non-autoimmune inflammatory diseases, including both acute and chronic infections.